Wolfram syndrome is a rare genetic disorder that primarily affects the nervous system and pancreas. A specific subtype — Ashkenazi Jewish WFS1-Associated Wolfram syndrome — primarily impacts individuals of Ashkenazi Jewish descent.
Learn more about the unique features that distinguish the Ashkenazi variant.
Common Symptoms
Ashkenazi Jewish WFS1-Associated Wolfram syndrome can cause vision loss, atypical diabetes, urinary issues and neurological concerns. Learn more about potential symptoms now.
Washington University in St. Louis’ internationally recognized team is actively seeking new patients to join their clinical care and research efforts. Join the Wolfram Syndrome International Registry to learn about clinical studies and genetic testing opportunities.
Jewish Wolfram syndrome is a recessive condition — both parents must be carriers for a child to be affected. Learn more about genetic inheritance, family planning, carrier testing and reproductive options.
